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1N94:
Aryl Tetrahydropyridine Inhbitors Of Farnesyltransferase: Glycine, Phenylalanine And Histidine Derivates
PDB ID:
1N94
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MMDB ID:
21854
PDB Deposition Date:
2002/11/22
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
3.5 Å
Source Organism:
Rattus norvegicus
Similar Structures:
VAST+
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Biological Unit for 1N94: dimeric; determined by author and by software (PISA)
Molecular Components in 1N94
Label
Count
Molecule
Proteins (2 molecules)
A
1
Protein Farnesyltransferase Alpha Subunit
(Gene symbol:
Fnta
)
B
1
Protein Farnesyltransferase Beta Subunit
(Gene symbol:
Fntb
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Alpha-Hydroxyfarnesylphosphonic Acid
2
1
2-{(5-{[butyl-(2-Cyclohexyl-Ethyl)-Amino]-Methyl}-2'-Methyl-Biphenyl-2-Carbonyl)-Amino]-4-Methylsulfanyl-Butyric Acid
3
1
Zinc Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303